BEMÆRK: Ansøgningsfristen er overskredet
Faculty of Health and Medical Sciences
University of Copenhagen
We are looking for a highly motivated and dynamic postdoc for a 2-year position (with possibility of extension), to commence 1 October 2023 or as soon as possible thereafter.
Information on the department can be found at: https://drug.ku.dk
In this project:
We aim to provide a fundamental understanding of glutamine transport mechanisms mediated by lysosomal sodium-coupled neutral amino acid transporters, SNAT7 and SNAT9, in health and disease. The project is built on an integrative approach of cryo-electron microscopy, cell-based, and in vitro studies.
Our research:
The ASH-Lab studies human membrane proteins involved in transport of amino acids, characterizing their structure, function, and mechanism of regulation to exploit their therapeutic potential.
Our lab uses Insect cells and mammalian expression systems to recombinantly express the target proteins and employs single-particle cryo-electron microscopy (cryo-EM) and serial synchrotron crystallography (SSX) combined with biochemical and biophysical methods to characterize the targets.
We are a growing international group at the University of Copenhagen with diversity and equity as our important priorities, keeping quality as the defining criterion.
The ASH-Lab is funded by Lundbeck Foundation and Novo Nordisk Foundation.
Your job
Your tasks would be to perform experimental research to understand how membrane proteins belonging to the lysosomal SLC38 family of transporters are regulated in health and disease using single particle cryo-EM and functional studies. You should be creative, with good interpersonal and collaborative skills, power of initiative, and a high degree of independence.
Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:
Essential experience and skills:
- You have a PhD in protein biochemistry, structural biology or similar.
- You have proficient communication skills and ability to work independently and in teams.
- You have excellent English skills (written and spoken)
- You are experienced in molecular biology, protein purification (preferably membrane proteins) and functional and biochemical characterisation.
- You have experience in working with mammalian/insect cell expression systems.
- You have experience with structural biology techniques (X-ray crystallography, cryo-EM or cryo-ET).
- Driving the project.
- Developing experimental protocols and pipelines.
- Daily supervision of junior researchers and students.
- Presenting your work in local, national, and international meetings and conferences.
- Having active interest in applying for research funding.
The place of employment is at the Department of Drug Design and Pharmacology, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment.
The project will be based within the Peptides and Proteins Discipline at ILF–KU, which has an excellent infrastructure for protein production and purification including eukaryotic and bacterial cell labs, centrifuges, ultracentrifuges, various protein liquid chromatography platforms (AKTA systems), liquid handling robotics, including a Gryphon robot critical for setting up lipidic cubic phase experiments, and plunge freezers for cryo-EM sample preparation. The ASH-Lab has regular access to high-end Cryo-EM facilities in Copenhagen and Aarhus through CryoNET (https://krios-denmark.ku.dk/cryonet/).
Terms of employment
The average weekly working hours are 37 hours per week.
The position is a fixed-term position limited to a period of 2 years (with possibility of extension). The starting date is 1 October 2023 or as soon as possible thereafter upon agreement.
Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 36,000 DKK/approx. 4,830 EUR (April 2023 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.
Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.
The position is covered by the Job Structure for Academic Staff at Universities 2020.
Questions
For further information please contact Azadeh Shahsavar; ash@sund.ku.dk
Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).
Application procedure
Your online application must be submitted in English by clicking ‘Apply now’. Furthermore, your application must include the following documents/attachments – all in PDF format:
- Motivated letter of application (max. one page).
- CV incl. education, work/research experience, language skills and other skills relevant for the position and the contact information of minimum of two academic references, one of which should be your current or most recent supervisor.
- A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
- List of publications.
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/
The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.
INFORMATIONER OM STILLINGEN:
- Arbejdspladsen ligger i:
Gladsaxe Kommune
-Virksomheden tilbyder:
-Arbejdsgiver:
KU - SUND - Kbh Ø , Institut for Farmaci, Universitetsparken 2, 2100 København Ø
-Ansøgning:
Ansøgningsfrist: 12-07-2023; - ansøgningsfristen er overskredet
Ved skriftlig henvendelse: https://candidate.hr-manager.net/ApplicationInit.aspx?cid=1307&ProjectId=159564&DepartmentId=19218&MediaId=4632&SkipAdvertisement=true
Se mere her: https://job.jobnet.dk/CV/FindWork/Details/5857309