BEMÆRK: Ansøgningsfristen er overskredet
We are looking for a highly motivated and dynamic bioinformatician to join our group and extensive industry & clinical networks to understand genomic changes in the human germline that result in miscarriage and congenital disorders in humans. The position is for 4 years to commence on 1 September 2023, or after agreement.
Information about the Department of Cellular and Molecular Medicine (ICMM) can be found at: https://icmm.ku.dk/english/.
Our research
We develop and utilize statistical models, machine learning and imputation algorithms that allow us to map human recombination events and chromosomal aberrations in human embryos and eggs in high resolution. We integrate our tools with existing approaches to create a high throughput computational pipeline running on a computer cluster. The output of this pipeline provides us with features of human meiosis that we further combine with existing genomics data using simulation experiments.
The information from our data science experiments and pipelines help us to answer about what drives human meiosis and what are the factors and patterns that can lead to chromosomal errors.
Information about the Hoffmann group can be found at: www.icmm.ku.dk/english/research-groups/hoffmann-group/.
Your job
Key responsibilities:
- Develop and run pipelines for genetic analyses of human embryos and oocytes in HPC environment.
- Test and implement extensions to our in-house algorithms for phasing as well as detection of meiotic recombination sites and chromosomal aberrations in embryos.
- Simulation analyses on the data, including integration with population genetics.
- Communicate results of the data analyses using reports and visualization tools for high-end publications.
We are looking for a highly motivated and enthusiastic individual with the following competencies and experience:
Essential experience and skills:
- Experience with implementing statistical and machine learning models on (single cell) genomics data.
- Extensive knowledge of Python.
- Proficiency in R and bash.
- Hands on experience with data science tools and packages such as pandas, scikit, seaborn, ggplot, Jupyter notebook.
- Experience working with git.
- Experience with bioinformatics workflow management systems such as snakemake.
- Experience with computing on HPC and using scheduling systems such as slurm.
- Experience working with SNP arrays and preferably whole genome sequencing data.
- Data management plans and curation required for publications in high impact journals.
- Basic knowledge of human genetics and human meiosis.
- Ability to communicate and collaboration with wetlab scientists and computational scientists.
- You have a PhD in bioinformatics or machine learning or with a significant component thereof.
- Experience from similar positions such as Bioinformatic Platforms / Core facilities.
The employment as a bioinformatician is a full-time position (37 working hours per week in average) and a fixed-term position for 4 years. Starting date is 1 September 2023, or after agreement.
Employment will be in accordance with the provisions of the collective agreement between the Danish Ministry of Taxation and AC (the Danish Confederation of Professional Associations). The monthly salary will be based on the number of years of work experience (seniority), with the possibility to negotiate a salary supplement based on prior experiences and qualifications. The employer will pay an additional 17.1 % to your pension fund.
Depending on experience and qualifications, the employment will be as either an Academic Research Staff, an Academic Officer, or a Research Consultant.
Questions
For further questions about the job description and qualifications, please contact Professor Eva Hoffmann by e-mail: eva@sund.ku.dk.
Foreign applicants may find the following links useful: https://ism.ku.dk/ (International Staff Mobility) and workindenmark.dk.
Application
Your application must be submitted in English by clicking on ‘Apply online’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:
- Motivation letter (max one page).
- Curriculum vitae.
- Copies of relevant diplomas/degree certificate(s) of education.
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The University of Copenhagen wishes to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.
INFORMATIONER OM STILLINGEN:
- Arbejdspladsen ligger i:
Gladsaxe Kommune
-Virksomheden tilbyder:
-Arbejdsgiver:
KU - SUND - PANUM KBH N, Blegdamsvej 3B, 2200 København N
-Ansøgning:
Ansøgningsfrist: 30-07-2023; - ansøgningsfristen er overskredet
Ved skriftlig henvendelse: https://candidate.hr-manager.net/ApplicationInit.aspx?cid=1307&ProjectId=159641&DepartmentId=19000&MediaId=4632&SkipAdvertisement=true
Se mere her: https://job.jobnet.dk/CV/FindWork/Details/5866321